Post-Doctoral Researcher

The petitioner proposes to continue research in structural biology and drug discovery, specifically focusing on the three-dimensional structures of human membrane proteins linked to rare diseases. This work involves using cryo-electron microscopy and mammalian host cells to identify critical features for developing innovative antibodies and small-molecule inhibitors. The goal is to advance targeted treatment strategies for infectious diseases, cancer, and rare conditions.

The petitioner proposes to continue using molecular cloning, protein expression and purification, and biochemistry assays to advance knowledge of the structure of cell surface receptors. Her work focuses on deepening the fundamental understanding of biological systems to pave the way for developing targeted therapeutics for diseases such as cancer.

The petitioner proposes to investigate the molecular processes of protein misfolding to advance therapeutic strategies for neurodegenerative disorders, cancer, and diabetes. His work focuses on identifying how aberrant protein structures can be corrected or leveraged to design cost-effective treatment platforms grounded in structural biochemistry.

The petitioner proposes to continue research in structural biology, specifically elucidating the molecular mechanisms underlying biological processes involved in diseases. The work utilizes cryo-electron microscopy (cryo-EM) and NMR spectroscopy to understand proteins and receptors related to neurodegenerative diseases, cancer, and pathogenic bacteria to develop novel therapeutic strategies.